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荣湘江,张 娟,梁丹丹.运动对大鼠胰岛素样生长因子-Ⅰ影响的研究[J].中国康复医学杂志,2008,23(5):423~425
运动对大鼠胰岛素样生长因子-Ⅰ影响的研究    点此下载全文
荣湘江  张 娟  梁丹丹
首都体育学院保健康复教研室,北京北三环西路11号,100088
基金项目:北京市教委2005年科技类面上项目(KM200510029001)
DOI:
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摘要:
      目的:探讨运动对胰岛素样生长因子-Ⅰ的影响,并研究运动与血清IGF-Ⅰ的相关性。方法:将104只45日龄SD雄性大鼠随机分为4组,分别为对照组、实验1、2、3组,实验组做同一速度、不同持续时间(15、30、60min)的跑台运动,分时间段采血检测各组血清IGF-Ⅰ的浓度。结果:①实验组运动后即刻大鼠血清IGF-Ⅰ值升高,与对照组相比差异有显著性(P<0.05),但是与运动强度不呈完全的线性关系。②大鼠血清IGF-Ⅰ运动后呈现先升高再下降的趋势,最高值(410.52±12.44)出现在30min跑台运动后休息10min时。结论:运动使大鼠血清IGF-Ⅰ值升高,但与运动强度、运动时间不完全相关。
关键词:运动  运动持续时间  胰岛素样生长因子-Ⅰ
Research about the effect of sport on insulin-like growth factor-Ⅰ of rats    Download Fulltext
The Studies′ Section of Health Care and Rehabilitation of Sports of Capital Institute of Physical Education, Beijing, 100088
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Abstract:
      Objective: To research the correlation between sport and seram concentration of insulin-like growth factor-Ⅰ(IGF-Ⅰ). Method: SD rats were randomly separated into four groups: control group and experimental 1,2,3groups. Experimental groups were engaged to do exercises for various duration(15, 30, 60min) with the same speed. Then serum concentration of IGF-Ⅰ in each of experiment period were detected. Result:①Compared with control group,sport would elevate the serum concentration of IGF-Ⅰ significantly, but it was not complete linear relationship between serum IGF-Ⅰ and exercises intensity.②The trend of changing of IGF-Ⅰwas increasing at first and then going down, maximum of IGF-Ⅰwas 410.52±12.44 appearing at resting for 10min after 30min exercises on treadmill.Conclusion:Sport would elevate the serum concentration of IGF-Ⅰ, but was not relative to exercises intensity and duration.
Keywords:sport  exercises duration  insulin-like growth factor-Ⅰ
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