设为首页
加入收藏
联系我们
Email-Alert
 

    首页 | 杂志介绍 | 编委成员 | 投稿指南 | 订阅指南 | 过刊浏览 | 论著模板 | 综述模板 | 帮助

 
李红卫,江钟立,吴亚文,陈 玲.运动训练对糖尿病大鼠尾神经传导速度的影响[J].中国康复医学杂志,2009,24(5):412~415
运动训练对糖尿病大鼠尾神经传导速度的影响    点此下载全文
李红卫  江钟立  吴亚文  陈 玲
南京医科大学第一附属医院康复医学科,210029
基金项目:
DOI:
摘要点击次数: 2645
全文下载次数: 2374
摘要:
      目的:探讨运动训练对糖尿病大鼠尾神经传导速度(CNCV)的影响。方法:链脲霉素(STZ,55mg/kg)诱导的21只糖尿病大鼠随机平均分配到糖尿病运动8周组(A)、糖尿病运动4周组(B)和糖尿病对照组(C),实验结束时17只糖尿病大鼠存活,其中A组6只、B组6只和C组5只;12只正常血糖大鼠随机分为正常运动8周组(D,n=6)和正常对照组(E,n=6)。运动组大鼠游泳60min/d,5d/周。实验过程中分别于基线、第4周、第8周时测定大鼠血糖、体重和CNCV。结果:糖尿病大鼠基线时血糖显著高于正常血糖大鼠
关键词:运动训练  糖尿病神经病变  尾神经传导速度
The effect of exercises training on caudal nerve conduction velocity in diabetic rats    Download Fulltext
Department of Rehabilitation Medicine, the First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029
Fund Project:
Abstract:
      Objective: To explore the effect of exercises on caudal nerve conduction velocity(CNCV) in streptozotocin-induced diabetic rats. Method: Twenty-one diabetic rats induced by streptozotocin(STZ, 55mg/kg) were randomly divided into diabetic group A with exercises for 8 weeks, diabetic group B with exercises for 4 weeks and diabetic control group C without exercises. Seventeen diabetic rats survived at the end of experiment, which were distributed respectively in group A(n=6), group B(n=6) and group C(n=5). Twelve SD rats with euglycemia were randomly divided into normal exercises 8 weeks group D(n=6) and normal control group E(n=6). The exercises rats were forced to swim 60min/d with 5d/week. Body weights, blood glucose and CNCV in all rats were evaluated at the points of baseline, the 4th week and 8th week. Result: Blood glucose in diabetic rats were higher than that in rats with euglycemia (P<0.05). Blood glucose in group A decreased significantly after 8 weeks exercises in comparison with baseline (P<0.05). The CNCV were significantly lower in all diabetic groups than that in groups with euglycemia and were significantly higher in group A than those in groups B and C at the 4th week. The CNCV in groups A and B increased significantly beyond baseline(P<0.05) and to normal level as the groups with euglycemia at the 8th week. The CNCV in group C at the 8th week decreased significantly in comparison with baseline (P<0.05). The CNCV in groups D and E at the 8th week increased significantly in comparison with baseline. Conclusion: Exercises training may prevent and treat the diabetic neuropathy.
Keywords:exercises training  diabetic neuropathy  caudal nerve conduction velocity
查看全文  查看/发表评论

您是本站第 37824489 位访问者

版权所有:中国康复医学会
主管单位:中国科学技术协会 主办单位:中国康复医学会
地址:北京市朝阳区樱花园东街,中日友好医院内   邮政编码:100029   电话:010-64218095   

本系统由北京勤云科技发展有限公司设计
京ICP备18060696号-2

京公网安备 11010502038612号