脊髓损伤致不同肢体瘫痪类型青壮年女性血脂水平对比研究

关键词：青壮年女性  双下肢瘫  四肢瘫  脊髓损伤  血脂

Keywords:young female  paraplegia  tetraplegia  spinal cord injury  serum lipid

摘要：

      摘要 目的：通过比较脊髓损伤致双下肢瘫和四肢瘫青壮年女性血脂水平，探讨这些患者血脂差异的可能机制。 方法：对中国康复研究中心2004—2008年因脊髓损伤导致肢体瘫痪进行康复治疗的女性患者进行入院状态调查。入选要求：①病史明确（脊髓损伤致肢体瘫痪）；②资料完整；③18周岁≤年龄≤60岁；④非卒中患者。共270例患者入选，对血脂指标（甘油三酯,TG；总胆固醇,TC；低密度脂蛋白,LDL；高密度脂蛋白，HDL）进行比较分析。 结果：双下肢瘫者与四肢瘫患者相比TG和HDL水平显著较高(TG 1.56mmol/L比1.36mmol/L;HDL 1.15mmol/L比1.03mmol/L)，TC和LDL水平无显著差异。四肢瘫者HDL降低发生率显著高于双下肢瘫者。 结论：青壮年女性上肢活动功能与TG和HDL代谢有关，正常上肢活动功能有助于HDL水平的提高。

Abstract:

      Abstract Objective: To study the difference of serum lipids level between paraplegic and tetraplegic in Chinese women. Method: There were 270 female spinal cord injury (SCI) patients admitted in China Rehabilitaion Research Center (CRRC) for rehabilitation therapy from Jan 2004 to Dec 2008 were investigated. The enrolled criterias were: ①definite SCI history;②complete data;③18 years≤age≤60 years; ④non stroke. Lipid profiles included TG, TC, LDL, and HDL. SPSS13.0 was used for analysis. Result: Women with chronic paraplegia had higher TG and HDL levels (TG 1.56mmol/L vs 1.36mmol/L;HDL 1.15mmol/L vs 1.03mmol/L) than those with chronic tetraplegia. There was no significant difference in TC and LDL between paraplegics and tetraplegics. Women with chronic tetraplegia had higher prevalence of low HDL than those with chronic paraplegia. Conclusion: Upper extremities exercise may provide effects on metabolism of TG and HDL.