慢性神经病理痛患者生存质量及相关因素分析

关键词：神经病理痛  生存质量  疼痛  康复

Keywords:neuropathic pain  quality of life  pain  rehabilitation

摘要：

      摘要 目的：描述慢性神经病理痛患者的生存质量并分析相关的影响因素。 方法：采用简明疼痛调查表中文版（BPI-C）、健康状况问卷（SF-36）和自设休闲活动参与情况问卷，调查153例慢性神经病理痛患者的生存质量、平均疼痛程度、休闲活动情况等。 结果：慢性神经病理痛患者SF-36各维度得分均明显低于国内常模水平（P＜0.001）。影响SF-36生理综合分的因素有平均疼痛程度（β=-0.408，P＜0.001）、疼痛部位即头部/非头部（β=0.283，P＜0.001）、活动参与方式即主动/被动（β=0.197，P=0.004）；影响SF-36心理综合分的因素有平均疼痛程度（β=-0.346，P＜0.001）、疼痛部位即头部/非头部（β=0.215，P＜0.001）、活动参与方式即主动/被动（β=0.162，P=0.028）、单次活动时间即是否多于30min（β=-0.150，P=0.042）。患者的疼痛程度在不同的活动参与方式和活动时间的组间比较差异没有显著性意义。 结论：慢性神经病理痛患者生存质量较低，疼痛程度轻、疼痛部位以头部为主者生存质量较好，采用主动活动参与方式和相对较长的活动时间有助于提高其生存质量。

Abstract:

      Abstract Objective: To investigate the quality of life of patients with chronic neuropathic pain and to find the associated factors. Method: One hundred and fifty-three patients with chronic neuropathic pain without other chronic diseases or cancer were enrolled in a descriptive cross-sectional study by using short form 36-item questionnaire (SF-36) and brief pain inventory of Chinese version (BPI-C). Result: The scores of SF-36 of these patients were significantly lower than that of the Chinese norms (P＜0.001). The multiple linear regression analysis showed that pain severity, pain site (head or not) and activity engagement (active or passive) made statistically significant contributions to predicting physical composite score of SF-36 (β=-0.408, P＜0.001, β=0.283, P＜0.001, β=0.197, P=0.004, respectively). And pain severity, pain site (head or not), activity engagement (active or passive) and duration of activity (over 30 min or not) made statistically significant contributions to predicting mental composite score of SF-36 (β=-0.346, P＜0.001, β=0.215, P＜0.001, β=0.162, P=0.028, β=-0.150, P=0.042, respectively). Conclusion: These findings indicate that quality of life of patients with chronic neuropathic pain were lower, but if the pain was lighter and located at head and they may have better quality of life, active and longer enrollment of activity may improve their quality of life.