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郁正红,李建华.A型肉毒毒素用于治疗旋转型痉挛性斜颈的表面肌电分析[J].中国康复医学杂志,2014,29(4):343~347
A型肉毒毒素用于治疗旋转型痉挛性斜颈的表面肌电分析    点此下载全文
郁正红  李建华
浙江中医药大学第二临床医学院,浙江杭州,310005
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摘要:
      摘要 目的:采用表面肌电图检测技术对A型肉毒毒素治疗旋转型痉挛性斜颈疗效评定的作用进行初步探讨。 方法:选取30例符合条件的旋转型痉挛性斜颈患者,于A型肉毒毒素注射前和注射两周后分别用表面肌电图采集痉挛严重侧的颈伸肌、胸锁乳突肌在最大等长收缩条件下的平均功率频率(MPF)、平均肌电值(AEMG)的变化并同时进行Tsui评分。 结果:治疗后痉挛严重侧肌肉的MPF值上升,与治疗前比较差异显著(P<0.05);治疗后痉挛严重侧肌肉的AEMG值下降,与治疗前比较差异显著(P<0.05);治疗后Tsui评分明显下降,与治疗前比较差异显著(P<0.01)。表面肌电图与Tsui 评分结论相符。 结论:表面肌电图可以作为一种即刻、量化、精确和客观评价A型肉毒毒素治疗旋转型痉挛性斜颈疗效的方法,具有较好的临床应用价值。
关键词:表面肌电图  A型肉毒毒素  旋转型痉挛性斜颈  Tsui评分
Effect of botulinum toxin A on rotational type spasmodic torticollis analysed by surface electromyography    Download Fulltext
The Second Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, 310005
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Abstract:
      Abstract Objective:To explore the applicability of surface electromyography(sEMG) in the assessment of clinical effectiveness of botulinum toxin A(BTX-A) on rotational type spasmodic torticollis. Method:Thirty rotational type spasmodic torticollis patients were selected for the study, the mean power frequency(MPF) and average EMG (AEMG)were recorded before injection, and at 2 weeks after injection of BTX-A in the more severe side of trapezius and sternocleidomastoid muscles during maximal voluntary isometric contractions. Meanwhile, the Tsui score was recorded before injection, and at 2 weeks after injection of BTX-A. Result:Two weeks after injection of BTX-A, the findings demonstrated that MPF increased significantly in the more severe side of trapezius and sternocleidomastoid muscles as compared to that before treatment (P<0.05). AEMG decreased significantly in the more severe side of trapezius and sternocleidomastoid muscles as compared to that before treatment(P<0.05).The Tsui score decreased significantly as compared to that before treatment(P<0.05). The conclusions of SEMG were consistent with that of Tsui score. Conclusion:According to all findings, sEMG may be used as an immediate,quantitative,accurate and objective tool for evaluation of therapeutic effect during the rehabilitation of rotational type spasmodic torticollis patient treated by BTX-A.
Keywords:surface electromyography  botulinum toxin A  rotational type spasmodic torticollis  Tsui score
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