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李世光,李 伟,高前进,王彦伟.力量训练对增龄性血管内皮功能的影响及机制[J].中国康复医学杂志,2015,(2):147~151
力量训练对增龄性血管内皮功能的影响及机制    点此下载全文
李世光  李 伟  高前进  王彦伟
石家庄学院体育学院运动人体科学实验中心,石家庄,050035
基金项目:石家庄学院科研平台启动基金项目(xJpT005)
DOI:
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摘要:
      摘要 目的:研究力量训练对老年人血管内皮功能和炎症因子的影响,探讨力量训练对增龄性血管内皮功能影响的机制。 方法:11例老年男性[平均年龄(70.63±3.93)岁]进行12周的力量训练,使用多普勒超声显像技术测定受试者运动训练前后的血流介导的内皮依赖性血管舒张功能(FMD),同时检测血清肿瘤坏死因子-α(TNF-α)、白细胞介素6(IL-6)、超敏C反应蛋白(hsCRP)、脂联素(adiponectin)。 结果:经过12周的力量训练后,老年人体脂率显著降低(P<0.05),血糖、血脂出现显著性下降,肌肉力量显著增加,同时FMD显著提高(P<0.05),而TNF-α、IL-6、hsCRP水平出现显著降低,adiponectin显著升高;FMD增加的程度与血清TNF-α、IL-6、hsCRP降低的程度,以及adiponectin升高的程度呈显著正相关。 结论:12周的力量训练提高了老年人血管内皮功能,减低了炎症反应水平;力量训练提高老年人血管内皮功能与炎症水平下降有关,这可能是力量训练提高老年人心血管机能的机制之一。
关键词:力量训练  老年男性  血流介导血管舒张功能  血管内皮功能  炎症因子水平
Effects of strength training on aging vascular endothelial function and related mechanisms    Download Fulltext
Human Movement Science Experimental Center,Shijiazhuang College,Sport College,050035
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Abstract:
      Abstract Objective: To investigate the effects of strength training on vascular endothelial function and inflammatory factors levels in elderly men, to explore the possible mechanisms of strength training improving aging vascular endothelium. Method: Eleven elderly men [(70.63±3.93)years] participated in 12 weeks resistance training. Before and after exercise intervention, ultrasound technique was used to detect the flow mediate dilation (FMD), and the serum levels of TNF-α, IL-6, hsCRP and adiponectin were detected. Result: After strength training, the percentage of body fat and blood glucose showed significant decline, muscle strength showed significant increase, FMD showed significant increase, while the serum TNF-α, IL-6, and hsCRP levels showed significant decrease, as well as adiponectin levels showed significant increase; the positive correlations between increase of FMD and decrease of levels of TNF-α, IL-6, hsCRP, as well as increase of levels of adiponectin were found. Conclusion: Strength training could improve aging vascular endothelial function associated with reducing the levels of anti-inflammation factors, this may be the mechanism of strength training.
Keywords:strength training  elderly men  flow mediate dilation  vascular endothelial function  inflammatory factor level
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