不同强度有氧运动对经皮冠状动脉介入治疗术后患者心功能及运动耐力的影响

关键词：有氧运动  经皮冠状动脉介入治疗  心功能  运动耐力

Keywords:aerobic exercise  percutaneous coronary intervention  cardiac function  exercise endurance

摘要：

      摘要 目的：探讨不同强度有氧运动对经皮冠状动脉介入治疗（PCI）术后患者心功能及运动耐力的影响。 方法：将65例PCI术后患者随机分为高强度（峰值功率的80%）间歇有氧运动组(22例)、中等强度（峰值功率的60％）有氧运动组（21例）、对照组（22例）。高强度运动组以3min训练、1min休息的间歇训练模式进行，每次训练10组，共40min。中等强度运动组每次持续训练40min，两组患者均训练12周，每周3次，所有患者训练前后均行超声心动图及心肺运动试验（CPET）评估患者心功能及运动耐力。 结果：训练前3组患者的左室射血分数（LVEF）、峰值功率(PP)、运动持续时间(ED)、峰值摄氧量(VO2peak)、无氧阈(AT)均无显著差异（P＞0.05）；训练后高强度运动组及中等强度运动组PP、ED、VO2peak比较差异具有显著性（P＜0.05），且均优于对照组（P＜0.05）；中等强度运动组与对照组LVEF差异并无显著性（P＞0.05），但均与高强度运动组有显著差异（P＜0.05）;AT仅高强度运动组比对照组明显增高（P＜0.05）。 结论：与中等强度持续有氧运动相比，高强度间歇有氧运动可以更好地改善PCI术后患者的左室收缩功能及有氧代谢能力，提高患者的运动耐力。

Abstract:

      Abstract Objective： To investigate the effects of different intensity aerobic exercise on cardiac function and exercise endurance in patients after percutaneous coronary intervention (PCI). Method：Sixty-five patients after PCI were randomly divided into high-intensity (80% of peak power) intermittant aerobic exercise group (n=22), moderate-intensity (60% of peak power) aerobic exercise group (n=21) and control group (n=22). High-intensity exercise training group performed by the mode of 3min training separated by 1min of rest, 10 sessions every time,each time lasted 40min， moderate-intensity exercise group accepted 40min persistent training every time. All patients trained for 12 weeks, 3 times a week, before and after training, all patients received echocardiography and cardiopulmonary exercise test(CPET) to assess their cardiac function and exercise endurance. Result： Before training, 3 groups of patients had no significantly difference (P>0.05) in left ventricular ejection fraction (LVEF), peak power (PP), exercise duration (ED), peak oxygen uptake (VO2peak) and anaerobic threshold (AT); after training, there were significant differences (P<0.05) between high-intensity exercise group and moderate-intensity exercise group in PP, ED, VO2peak, and all were better than control group (P<0.05); moderate-intensity exercise group and control group had no significant difference in LVEF (P>0.05), but there were significant differences (P<0.05) to high-intensity exercise group; only high-intensity group had significantly higher AT than control group (P<0.05). Conclusion： Compared with continuous moderate-intensity aerobic exercise, high-intensity intermittent aerobic exercise can better improve left ventricular systolic function and aerobic metabolism ability of patients after PCI, and improve their exercise tolerance.