轻中度青少年特发性脊柱侧凸患者肺功能研究

关键词：青少年  特发性  脊柱侧凸  肺功能

Keywords:adolescent  idiopathic  scoliosis  pulmonary function

摘要：

      摘要 目的：研究轻中度青少年特发性脊柱侧凸（adolescent idiopathic scoliosis,AIS）患者肺功能特征。 方法：选取68例AIS患者作为AIS组，20例健康青少年作为正常对照组，采用肺功能仪测定研究对象用力肺活量（FVC）、FVC预计值（FVC pred）、FVC占预计值百分数（FVC pred%）、第1秒用力呼气量（FEV1）、FEV1预计值（FEV1 pred）、FEV1占预计值百分数（FEV1 pred%）、FEV1占FVC百分数（FEV1/FVC%）。 结果：AIS组FEV1 pred%、FEV1/FVC%分别为（85.60±11.60）、（88.40±6.84），对照组分别为（93.20±9.39）、（91.00±3.13），AIS组FEV1 pred%、FEV1/FVC%均低于正常对照组，差异有显著性意义。不同侧凸类型、不同性别AIS患者FVC pred%、FEV1 pred%、FEV1/FVC%差异无显著性意义。患者年龄与FVC、FVC pred、FEV1、FEV1 pred正相关，患者Cobb角与肺功能指标无关。 结论：轻、中度AIS患者存在肺功能障碍，患者肺功能与年龄正相关，与侧凸类型、性别、Cobb角没有相关性。

Abstract:

      Abstract Objective: To investigate the pulmonary function of mild-to-moderate adolescent idiopathic scoliosis (AIS) patients. Method: For this study, 68 AIS patients and 20 healthy subjects were recruited. Forced vital capacity (FVC), FVC pred, FVC pred%, forced expiratory volume in first second (FEV1), FEV1 pred, FEV1 pred%, and FEV1/FVC% of normal subjects and AIS patients were measured. Result: FEV1 pred% and FEV1/FVC% of AIS patients were (85.60±11.60) and (88.40±6.84), meanwhile those of normal subjects were (93.20±9.39) and (91.00±3.13). Compared with normal controls, AIS had lower FEV1 pred% and FEV1/FVC%. No significant difference in FVC pred%, FEV1 pred% and FEV1/FVC% was found among different curve patterns and gender of AIS patients. There was a positive correlation between FVC, FVC pred, FEV1, FEV1 pred and age in AIS patients. However, there was no correlation between pulmonary function and Cobb angle in AIS patients. Conclusion: Mild-to-moderate AIS patients have pulmonary dysfunction generally. The pulmonary function has a positive correlation with the age, but no correlation with the curve pattern, gender and Cobb angle in mild-to-moderate AIS patients.