基于呼吸-交感神经偶联机制的呼吸训练对于脑卒中患者血压影响的研究

关键词：呼吸-交感神经偶联  血压  呼吸训练

Keywords:respiratory-sympathetic coupling  blood pressure  respiratory training

摘要：

      摘要 目的：拟采用呼吸训练结合常规康复训练，观察脑卒中患者血压的变化，探索呼吸训练对于脑卒中患者血压的影响。 方法：以2021年1月至2021年12月在黑龙江中医药大学附属第二医院康复中心进行治疗的脑卒中并伴有高血压患者40例，随机分为训练组、对照组。对照组20例患者接受常规治疗，训练组20例患者在常规治疗基础上增加呼吸训练，训练2周后，测定血压、心率、肾素、血管紧张素Ⅱ、醛固酮水平数据。 结果：在康复训练2周后，训练组血压、心率低于对照组（P＜0.05）；肾素、血管紧张素Ⅱ、醛固酮水平数据好于对照组（P＜0.05）。 结论：呼吸训练对脑卒中患者血压有降压的效果，其作用机制可能是通过主动呼吸调整呼吸-交感神经偶联机制中的肾素-血管紧张素-醛固酮系统，具体机制有待进一步深入探讨。

Abstract:

      Abstract Objective： To observe the changes of blood pressure in stroke patients by combining breathing training with conventional rehabilitation training，and explore the effect of breathing training on blood pressure in stroke patients. Method： A total of 40 stroke patients with hypertension who were treated in the Rehabilitation Center of the Second Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine from January 2021 to December 2021 were randomly divided into two groups， training group and control group. Twenty patients in the control group received routine rehabilitation training， while 20 patients in the training group received breathing training on the basis of routine rehabilitation training. After 2 weeks of training， the levels of blood pressure， heart rate， renin， angiotensin Ⅱand aldosterone were measured. Result： After 2 weeks of rehabilitation training， the blood pressure and heart rate of the training group were lower than those of the control group， and the levels of renin， angiotensin Ⅱ and aldosterone were better than those of the control group， （P<0.05）. Conclusion： Respiratory training is effective to lower blood pressure in stroke patients， and its mechanism may be related to the adjustion of the renin-angiotensin-aldosterone system in the respiratory-sympathetic coupling mechanism through active breathing. The specific mechanism needs to be further explored.