脑挫裂伤失语症患者高压氧不同压力的治疗效果

关键词：高压氧治疗  脑挫裂伤  失语症  波士顿诊断性失语症评定

Keywords:hyperbaric oxygen therapy  cerebral contusion  aphasia  Boston diagnostic aphasia examination

摘要：

      摘要 目的：探索不同压力高压氧治疗脑挫裂伤后失语症患者的治疗效果。 方法：对90例脑挫裂伤后失语症患者按入组时间顺序随机分成3组，对照组给予常规的脑外科综合治疗，治疗组在采用综合治疗基础上，治疗1组采用0.18MPa压力，治疗2组采用0.20MPa压力的高压氧治疗，高压氧1个疗程治疗10d，中间休息2d，共3个疗程。观察治疗前、每个疗程结束后3个组波士顿诊断性失语症（BDAE）的分级变化。 结果：经2和3个疗程治疗后，2个治疗组BDAE分级评价较对照组比较，差异有显著性意义(P＜0.05)。治疗1组和治疗2组之间在脑外伤失语症的治疗结果上比较差异无显著性意义(P＞0.05)。 结论： 高压氧治疗能促进脑挫裂伤失语症患者的言语功能恢复，患者经2—3个疗程治疗后其言语功能改善较明显，高压氧治疗压力0.18MPA和0.2MPA对脑挫裂伤失语症的治疗效果比较差异无显著性意义。建议采用0.18MPA的压力治疗脑挫裂伤后失语症可能更合适。

Abstract:

      Abstract Objective: To observe the effect of treatment of different hyperbaric oxygen（HBO） pressure on aphasia after cerebral contusion. Method: Ninety patients were recruited and divided into treatment group 1,group 2 and control group. Patients in control group received routine therapy. Patients in treatment group 1 and treatment group 2 received 0.18MPa and 0.2MPa pressure HBO therapy respectively beside routine therapy. The patients of group 1 and group 2 received three sessions of treatment in which each session lasted for 10d, with an interval of 2d between sessions. The effect of different HBO pressure therapy on aphasia after cerebral contusion was observed, before and after each session of HBO. Result: Boston diagnostic aphasia examination(BDAE) assessment showed significant difference between the two treatment groups and control group after 2 and 3 sessions of treatment. There was no obvious difference between treatment group 1 and treatment group 2 on the effect of aphasia after cerebral contusion (P>0.05). Conclusion: HBO therapy could promote the improvement of speech function of aphasia patients after cerebral contusion. The speech function improved more obviously after 2—3 months treatment, The effect of HBO therapy of 0.18MPA and 0.20MPA pressure was not statistically significant. HBO treatment of 0.18MPA pressure may be more appropriate for aphasia patients after cerebral contusion.